Joyti De-Laurey appeared before City of London Magistrates on Monday after being arrested last month. She is alleged to have transferred the money from two of Mead's personal bank accounts into an account at the Bank of Cyprus.
The charges detail one transfer of 2.25m on January 16 and another of 346,144 on April 12. The case was deferred until October 8.
Mead is one of the most successful bankers in London. He is Goldman's lead adviser to Vodafone, the mobile operator that is one of the bank's most lucrative clients. He worked on Vodafone's massive 115bn takeover of its German rival Mannesmann in 1999.
One report that he has a personal fortune of about 120m is thought to be excessive, but the 169bn of deals he has engineered for Vodafone and its subsidiaries, according to intelligence provider mergermarket.com, will have helped generate a considerable sum in bonuses.
Mead is a graduate from Harvard and Cambridge and is married with five children.
A spokesman for Goldman said: "A former employee has been charged with a theft of money from Scott Mead and the matter is in the hands of the police." He could not comment further.